|
DiagNano¢â Fluorophore Labeled Gold Nanoparticles
Creative Diagnostics provides
Fluorescent Gold Nanoparticles (AuNPs) labeled with various fluorophores for
multimodal imaging by dark-field scattering, fluorescence, as well as electron
microscopy. The fluorophore labeled gold nanoparticles exhibit both high
absorptions and scattering from gold nanoparticle as well as enhanced
fluorescence from the attached fluorophores. Gold nanoparticles significant enhance
the fluorescent signal and quantum yield of fluorophores based on the
metal-enhanced fluorescence (MEF) effect.
These nanoparticles are available
with the following fluorophores, IRDye 800, Alexa Fluor 750, Alexa Fluor 680,
Cy5.5, Alexa Fluor 647, Cy5, Alexa Fluor 633, Alexa Fluor 594, Texas Red, Alexa
Fluor 546, Alexa Fluor 555, FITC, Alexa Fluor 488.
Various active groups or ligands can
be chosen according to customer's need, including amine, biotin, carboxyl,
maleimide, methyl, neutravidin, NHS, streptavidin, MUTAB, protein A and
secondary antibodies. PEG or proprietary polymer is used as covalent polymer
bridge to the most popular in vitro terminations. For in vivo surface
terminations, a proprietary long circulating polymer would give the gold
nanoparticles ultra-long circulation time.
The fluorophore labeled AuNPs are
supplied in distilled water, PBS, Tris, Sodium Borate or MES; Other custom
buffers are also available on request.
Creative Diagnostics also offers a
series of fluorophore labeled AuNPs with specific cellular uptake ligands to
promote cellular uptake. These gold nanoparticles are non-toxic, suited
for in vivo application.
Custom conjugations are available
for special fluorophores, functional surfaces and molecules, such as
antibodies, proteins, peptides, lectins, etc.
Please do not hesitate to contact us
if you need free consultation and a detailed quotation of your project.
Applications:
Dual modal imaging by fluorescence and electron microscopy Increased fluorescence signal and higher quantum yield Increased stability in a wider pH range Lower background and higher signal-to-noise ratios Multiplex imaging for
different targets using different fluorophores
Products:
Á¦Ç°¿¡ ´ëÇÑ ÀÚ¼¼ÇÑ Á¤º¸´Â Ç°¸ñ Äڵ带 Ŭ¸¯ÇϽøé È®ÀÎÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù. ÀÔÀÚÇ¥¸éÀº ¿É¼Ç»çÇ×À¸·Î ÇØ´ç Á¦Ç°À¸·Î µé¾î°¡½Ã¸é ´Ù¾çÇÑ functional group, fluorophore ¹× buffer¸¦ ¼±ÅÃÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù.
|
Cat. No.
|
Description
|
Diameter
|
Absorption Max
|
Surface
|
Unit Size
| | GFL-1.8-NU | Fluorescent Gold Nanoparticles, Nuclei Uptake | 1.8 nm | N/A | Optional | 1 mL | | GFL-10 | Fluorescent Gold Nanoparticles | 10 nm | 514-520 nm | Optional | 1 mL | | GFL-100 | Fluorescent Gold Nanoparticles | 100 nm | 558 nm | Optional | 1 mL | | GFL-10-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 10 nm | 514-520 nm | Cellular uptake ligand | 1 mL | | GFL-125 | Fluorescent Gold Nanoparticles | 125 nm | 600 nm | Optional | 1 mL | | GFL-15 | Fluorescent Gold Nanoparticles | 15 nm | 514-520 nm | Optional | 1 mL | | GFL-150 | Fluorescent Gold Nanoparticles | 150 nm | 612 nm | Optional | 1 mL | | GFL-15-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 15 nm | 514-520 nm | Cellular uptake ligand | 1 mL | | GFL-2.2-NU | Fluorescent Gold Nanoparticles, Nuclei Uptake | 2.2 nm | N/A | Optional | 1 mL | | GFL-20 | Fluorescent Gold Nanoparticles | 20 nm | 514-520 nm | Optional | 1 mL | | GFL-200 | Fluorescent Gold Nanoparticles | 200 nm | N/A | Optional | 1 mL | | GFL-20-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 20 nm | 514-520 nm | Cellular uptake ligand | 1 mL | | GFL-25 | Fluorescent Gold Nanoparticles | 25 nm | 514-520 nm | Optional | 1 mL | | GFL-25-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 25 nm | 514-520 nm | Cellular uptake ligand | 1 mL | | GFL-30 | Fluorescent Gold Nanoparticles | 30 nm | 523 nm | Optional | 1 mL | | GFL-30-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 30 nm | 523 nm | Cellular uptake ligand | 1 mL | | GFL-35 | Fluorescent Gold Nanoparticles | 35 nm | 526 nm | Optional | 1 mL | | GFL-35-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 35 nm | 526 nm | Cellular uptake ligand | 1 mL | | GFL-3-NU | Fluorescent Gold Nanoparticles, Nuclei Uptake | 3 nm | N/A | Optional | 1 mL | | GFL-40 | Fluorescent Gold Nanoparticles | 40 nm | 527 nm | Optional | 1 mL | | GFL-40-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 40 nm | 527 nm | Cellular uptake ligand | 1 mL | | GFL-45 | Fluorescent Gold Nanoparticles | 45 nm | 529 nm | Optional | 1 mL | | GFL-45-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 45 nm | 529 nm | Cellular uptake ligand | 1 mL | | GFL-5 | Fluorescent Gold Nanoparticles | 5 nm | 505-508 nm | Optional | 1 mL | | GFL-50 | Fluorescent Gold Nanoparticles | 50 nm | 531 nm | Optional | 1 mL | | GFL-50-CU | Fluorescent Gold Nanoparticles, Cellular Uptake | 50 nm | 531 nm | Cellular uptake ligand | 1 mL | | GFL-55 | Fluorescent Gold Nanoparticles | 55 nm | 533 nm | Optional | 1 mL | | GFL-60 | Fluorescent Gold Nanoparticles | 60 nm | 536 nm | Optional | 1 mL | | GFL-65 | Fluorescent Gold Nanoparticles | 65 nm | 539 nm | Optional | 1 mL | | GFL-70 | Fluorescent Gold Nanoparticles | 70 nm | 542 nm | Optional | 1 mL | | GFL-75 | Fluorescent Gold Nanoparticles | 75 nm | 545 nm | Optional | 1 mL | | GFL-80 | Fluorescent Gold Nanoparticles | 80 nm | 549 nm | Optional | 1 mL | | GFL-85 | Fluorescent Gold Nanoparticles | 85 nm | 553 nm | Optional | 1 mL | | GFL-90 | Fluorescent Gold Nanoparticles | 90 nm | 558 nm | Optional | 1 mL | | GFL-95 | Fluorescent Gold Nanoparticles | 95 nm | 558 nm | Optional | 1 mL |
|
